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Items: 4

1.

Age-related epithelial defects limit thymic function and regeneration

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Other; Expression profiling by high throughput sequencing
Platform:
GPL24247
51 Samples
Download data: CLOUPE, CSV, H5, HTML, JSON, MTX, TAR, TIFF, TSV
Series
Accession:
GSE240020
ID:
200240020
2.

Age-related epithelial defects limit thymic function and regeneration [single cell]

(Submitter supplied) The thymus is essential for establishing adaptive immunity yet undergoes age-related involution that leads to compromised immune responsiveness. The thymus is also extremely sensitive to acute insult and although capable of regeneration, this capacity declines with age for unknown reasons. We applied single-cell and spatial transcriptomics, lineage-tracing and advanced imaging to define age-related changes in non-hematopoietic stromal cells and discovered the emergence of two atypical thymic epithelial cell (TEC) states. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
29 Samples
Download data: CSV, H5, H5AD, MTX, TSV
Series
Accession:
GSE240016
ID:
200240016
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

02-mo CD45- thymic fibroblasts - day 7 after SL-TBI [singe cell]

Organism:
Mus musculus
Source name:
thymus
Platform:
GPL24247
Series:
GSE240016 GSE240020
Download data: CSV, H5, MTX, TSV
Sample
Accession:
GSM7679884
ID:
307679884
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Supplemental Content

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