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Items: 4

1.

Functional mapping of Glioblastoma recurrence reveals targetable dependencies in an axonal guidance pathway in lethal brain cancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Other; Expression profiling by high throughput sequencing
Platform:
GPL24676
41 Samples
Download data: TXT
Series
Accession:
GSE240492
ID:
200240492

2.

Functional mapping of Glioblastoma recurrence reveals targetable dependencies in an axonal guidance pathway in lethal brain cancers [Genome-wide CRISPR-Cas9]

(Submitter supplied) Resistance to genotoxic therapies and tumor recurrence are hallmarks of glioblastoma (GBM), an aggressive brain tumor. Here, we explore functional drivers of post-treatment recurrent GBM. By conducting genome-wide CRISPR-Cas9 knockout screens in patient-derived GBM models, we uncover distinct genetic dependencies in recurrent tumor cells absent in their patient-matched primary predecessors, accompanied by increased mutational burden and differential transcript and protein expression. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL24676
21 Samples
Download data: TXT
Series
Accession:
GSE240418
ID:
200240418

PubMed Similar studies

3.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17049 Series
931958 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

4.

BT241.T0 [GBM_1]

Organism:
Homo sapiens
Source name:
BT241
Platform:
GPL24676
Series:
GSE240418 GSE240492
Download data: TXT
Sample
Accession:
GSM7697749
ID:
307697749

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db=gds|term=GSM7697749[Accession]|query=8|qty=2|blobid=MCID_67300c8caf5f2e3c116aa01d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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