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Items: 3

1.

Novel Transcriptome Profiling Analyses Demonstrate that Selective PPARg Modulators Display Attenuated and Selective Gene Regulatory Activity in Comparison with PPARg Full Agonists

(Submitter supplied) We conducted extensive transcriptome profiling studies to characterize 70 SPPARgMs and seven PPARg full agonists in 3T3-L1 adipocytes, and a subset of these ligands in adipose tissue of diabetic db/db mice. In both cases, the SPPARgMs generated attenuated gene regulatory responses, and their gene expression signatures were more enriched in metabolic pathways that are likely to mediate anti-diabetic efficacy than those of PPARg full agonists. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL13717
331 Samples
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Series
Accession:
GSE31222
ID:
200031222
2.

Rosetta/Merck Mouse 25k v1.2 extra microarray

(Submitter supplied) Oligonucleotide array on glass. Contains 60-mer probes (60-mer). Mouse 25k v1.2 extra microarray Merck Protocol: See manufacturer's website
Organism:
Mus musculus
3 Series
337 Samples
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Platform
Accession:
GPL13717
ID:
100013717
3.

E1_vehicle control pool vs PPARg full 1 (6 nM) #2

Organism:
Mus musculus
Source name:
E1_vehicle control pool (channel 1) PPARg full 1 (6 nM) #2 (channel 2)
Platform:
GPL13717
Series:
GSE31222
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Sample
Accession:
GSM770123
ID:
300770123
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Supplemental Content

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