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Items: 3

1.

Transcriptomic analyses of joint tissues during osteoarthritis development in a rat model reveal dysregulated mechanotransduction and extracellular matrix pathways

(Submitter supplied) Transcriptomic changes in joint tissues during the development of osteoarthritis (OA) are of interest for the discovery of biomarkers and mechanisms of disease. The objective of this study was to use the rat medial meniscus transection (MMT) model to discover stage and tissue-specific transcriptomic changes. Sham or MMT surgeries were performed in mature rats. Cartilage, menisci and synovium were scored for histopathological changes at 2, 4 and 6 weeks post-surgery and processed for RNA-sequencing. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32190
144 Samples
Download data: TXT
Series
Accession:
GSE241794
ID:
200241794
2.

NextSeq 2000 (Rattus norvegicus)

Organism:
Rattus norvegicus
16 Series
341 Samples
Download data
Platform
Accession:
GPL32190
ID:
100032190
3.

cartilage from rat (rat ID #11) with sham surgery 4 weeks post-surgery

Organism:
Rattus norvegicus
Source name:
cartilage
Platform:
GPL32190
Series:
GSE241794
Download data
Sample
Accession:
GSM7743814
ID:
307743814
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