GSM7777054[Accession] - GEO DataSets

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Items: 4

Select item 2002430061.

Metabolic adaptation pilots the differentiation of human hematopoietic cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL15520 GPL24676 GPL18573
63 Samples

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Series

Accession:: GSE243006

ID:: 200243006

PubMed Full text in PMC Similar studies

Select item 2002430032.

Metabolic adaptation pilots the differentiation of human hematopoietic cells (bulk ATAC-Seq)

(Submitter supplied) In order to get insight in the role of metabolic perturbations during the first steps of cell differentiation, the phenotype, gene expression profile and chromatin accessibility of CD34+ cells were examined using bulk- and single-cell techniques during the initial 96 hours of in vitro differentiation. Specific enzyme inhibitors targeting key steps of the energy metabolism were employed to induce perturbations and assess their effect. more...