GSM7781599[Accession] - GEO DataSets

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Items: 3

Select item 2002432431.

Off target expression data from iPSC derived microglia treated with APOE/TREM2 ASOs for 24h/48h. The iPSC cells are from a wild type donor (BIONi10C).

(Submitter supplied) Microglia play important roles in maintaining brain homeostasis and neurodegeneration. The discovery of genetic variants in genes predominately or exclusively expressed in myeloid cells, factors for Alzheimer’s disease (AD) highlights the importance of microglial biology in the brain. such as Apolipoprotein E (APOE) and triggering receptor expressed on myeloid cells 2 (TREM2), as the strongest risk factors for Alzheimer’s disease (AD) highlights the importance of microglial biology in the brain. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL31262
93 Samples

Download data: CEL

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Accession:: GSE243243

ID:: 200243243

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000312622.

[GO_Screen_hu] Affymetrix human GO_Screen_hu Assay

(Submitter supplied) This platform supports submissions for: GO_Screen_hu Applied Biosystems Clariom GO Screen Assay, human; Catalog number: 952361 Annotations: #%create_date=Mon Jun 24 16:48:33 PDT 2019 #%chip_type=GOScreen #%chip_type=GO_Screen_hu #%lib_set_name=GO_Screen_hu #%lib_set_version=r3 #%genome-species=Homo sapiens #%genome-version=hg38 #%genome-version-ucsc=hg38 #%genome-version-ncbi=GRCh38 #%genome-version-create_date=2013-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg38 #%genome-lifted_from-version-ncbi=GRCh38 #%netaffx-annotation-date=2016-06-03 #%netaffx-annotation-netaffx-build=36 #%netaffx-annotation-tabular-data-version=1.1 #%netaffx-annotation-tabular-format-version=1.1 #%netaffx-annotation-data-type=transcript_cluster #%netaffx-annotation-docgen-method=module:affy/annotation_update/builder; exec:create-download-file.pl #%netaffx-annotation-docgen-version=8487 #%guid=1154ed71-c66f-4d6b-8380-95763e360a91 ## probeset_id refers to the transcript cluster id, not the exon level probe set, and is required for ExACT software compatibility. more...