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Items: 4

1.

A functional genomics process for systematic dissection and mutation-specific target discovery in breast cancer PIK3CA hotspot mutations

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
21 Samples
Download data
Series
Accession:
GSE247822
ID:
200247822
2.

A functional genomics process for systematic dissection and mutation-specific target discovery in breast cancer PIK3CA hotspot mutations [ATAC-Seq]

(Submitter supplied) Despite the general understanding that different mutations impart different phenotypic changes within a cell, the majority of targeted therapies in cancer treatment are used to treat all mutations in the same gene regardless of location or phenotypic effects. There is a significant unmet need to distinguish distinct changes in cellular signaling which may provide opportunities for mutation-specific treatment with reduced toxicity to patients. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
6 Samples
Download data: NARROWPEAK
Series
Accession:
GSE247821
ID:
200247821
3.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
4.

MCF10A_WT_rep1_ATAC

Organism:
Homo sapiens
Source name:
Breast Epithelium
Platform:
GPL24676
Series:
GSE247821 GSE247822
Download data
Sample
Accession:
GSM7901246
ID:
307901246
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Supplemental Content

db=gds|term=GSM7901246[Accession]|query=2|qty=2|blobid=MCID_67135097c7d3ca20d549de56|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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