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Items: 3

1.

Non-Canonical BAF and mSWI/SNF Regulates POU2F3 and are Selective Targetable Dependencies for POU2F3-Positive Small Cell Lung Cancer

(Submitter supplied) ~12% of SCLCs are marked by the lineage transcription factor POU2F3, which is essential in all POU2F3-positive SCLCs. Thus, approaches to directly or indirectly inhibit POU2F3 could lead to new therapeutic strategies for POU2F3-positive SCLCs. Here we use a positive selection screening strategy where endogenous POU2F3 is fused to the suicide gene DCK*. Cells that express endogenous POU2F3-DCK* are killed in the presence of the nucleoside analog BVdU and only cells that downregulate the POU2F3-DCK* fusion survive. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL24676
125 Samples
Download data: BED, BW, TAB
Series
Accession:
GSE249362
ID:
200249362

PubMed Similar studies Analyze with GEO2R

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
16952 Series
930597 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

20231010_KSR035_RNA_NCIH211_DMSO_rep6

Organism:
Homo sapiens
Source name:
NCIH211
Platform:
GPL24676
Series:
GSE249362
Download data: BW, TAB
Sample
Accession:
GSM7937564
ID:
307937564

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db=gds|term=GSM7937564[Accession]|query=8|qty=2|blobid=MCID_6728253f9f58a261472c27d4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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