GEO DataSets

(Submitter supplied) The natural maintenance cycles of many mosquito-borne pathogens require establishment of persistent non-lethal infections in the invertebrate host. The mechanism by which this occurs is not well understood, but we have previously shown that an antiviral response directed by small interfering RNAs (siRNAs) is important in modulating the pathogenesis of alphavirus infections in the mosquito. However, we report here that infection of mosquitoes with an alphavirus also triggers the production of another class of virus-derived small RNAs that exhibit many similarities to ping-pong-dependent piwi-interacting RNAs (piRNAs). more...

Organism:

Aedes albopictus; Aedes aegypti

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL14594 GPL14595

20 Samples

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