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Items: 3

1.

Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants

(Submitter supplied) Nonsense and missense mutations in the transcription factor PAX6 cause a wide range of eye development defects, including aniridia, microphthalmia and coloboma. To understand how changes of PAX6:DNA binding cause these phenotypes, we combined saturation mutagenesis of the paired domain of PAX6 with a yeast one-hybrid (Y1H) assay in which expression of a PAX6-GAL4 fusion gene drives antibiotic resistance. more...
Organism:
Saccharomyces cerevisiae; synthetic construct
Type:
Other
Platforms:
GPL31112 GPL26302 GPL33815
15 Samples
Download data: CSV, TSV
Series
Accession:
GSE253580
ID:
200253580

2.

NextSeq 550 (Saccharomyces cerevisiae)

Organism:
Saccharomyces cerevisiae
52 Series
1404 Samples
Download data
Platform
Accession:
GPL26302
ID:
100026302

3.

LE9 assay timepoint 1 (12h without geneticin)

Organism:
Saccharomyces cerevisiae
Source name:
cell
Platform:
GPL26302
Series:
GSE253580
Download data
Sample
Accession:
GSM8023798
ID:
308023798

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db=gds|term=GSM8023798[Accession]|query=1|qty=3|blobid=MCID_666bcb736e9d376f23225efc|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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