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Items: 4

1.

The innate immune regulator MyD88 dampens fibrosis during zebrafish heart regeneration

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. The innate immune response is triggered rapidly after injury and its spatiotemporal dynamics are critical for regeneration, but many questions remain about its exact role. Here we show that MyD88, a key component of the innate immune response, controls not only the inflammatory but also the fibrotic response during zebrafish cardiac regeneration. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30614
14 Samples
Download data: TAR
Series
Accession:
GSE262248
ID:
200262248
2.

The innate immune regulator MyD88 dampens fibrosis during zebrafish heart regeneration (dst139)

(Submitter supplied) The innate immune response is triggered rapidly after injury and its spatiotemporal dynamics are critical for regeneration, but many questions remain about its exact role. Here we show that MyD88, a key component of the innate immune response, controls not only the inflammatory but also the fibrotic response during zebrafish cardiac regeneration. We find in cryoinjured myd88-/- ventricles a significant reduction in neutrophil and macrophage numbers as well as the expansion of a collagen-rich endocardial population. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30614
12 Samples
Download data: TXT
Series
Accession:
GSE262169
ID:
200262169
3.

NextSeq 2000 (Danio rerio)

Platform
Accession:
GPL30614
ID:
100030614
4.

injured tissue, myd88+/+, 1 hpci-2

Organism:
Danio rerio
Source name:
cardiac ventricles
Platform:
GPL30614
Series:
GSE262169 GSE262248
Download data
Sample
Accession:
GSM8159070
ID:
308159070
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db=gds|term=GSM8159070[Accession]|query=6|qty=2|blobid=MCID_6733e2b65c1af073747c59df|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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