GEO DataSets

(Submitter supplied) Death receptor-mediated hepatocyte apoptosis is implicated in a wide range of liver diseases including viral hepatitis, alcoholic hepatitis, ischemia/reperfusion injury, fulminant hepatic failure, cholestatic liver injury and cancer. Deletion of NF-ĸB essential modulator in hepatocytes (NemoΔhepa) causes the spontaneous development of hepatocellular carcinoma preceded by steatohepatitis in mice and thus serves as an excellent model for the progression from chronic hepatitis to liver cancer. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5332

Platform:

GPL6246

11 Samples

Download data: CEL

Analysis of livers from hepatocyte-specific NF-ĸB essential modulator (NEMO), NEMO-TRIAL, and NEMO-TNFR null males. NEMO deletion in hepatocytes causes spontaneous hepatocyte apoptosis. TNFR1 and TRAIL encode death receptors. Results provide insight into the role of death receptors in liver injury.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 4 genotype/variation sets

Platform:

GPL6246

Series:

GSE33161

11 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Mus musculus

143 DataSets

2504 Series

28 Related Platforms

30419 Samples

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