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1.

Developmental origins of Parkinson’s disease risk: developmental exposure to the organochlorine pesticide dieldrin leads to sex-specific DNA modifications in critical neurodevelopmental pathways in the mouse midbrain

(Submitter supplied) Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson’s disease (PD). Animal studies support a link between developmental dieldrin exposure and increased neuronal susceptibility in the α-synuclein preformed fibril (α-syn PFF) and MPTP models in adult male C57BL/6 mice. In a previous study, we showed that developmental dieldrin exposure was associated with sex-specific changes in DNA modifications within genes related to dopaminergic neuron development and maintenance at 12 weeks of age. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL24247
150 Samples
Download data: COV
Series
Accession:
GSE264165
ID:
200264165

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13894 Series
689629 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

701DNA

Organism:
Mus musculus
Source name:
Mouse midbrain
Platform:
GPL24247
Series:
GSE264165
Download data: COV
Sample
Accession:
GSM8213296
ID:
308213296

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db=gds|term=GSM8213296[Accession]|query=1|qty=2|blobid=MCID_6709e7e4475a635e85b765ab|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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