GSM8250427[Accession] - GEO DataSets

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Items: 4

Select item 2002665641.

Perivascular and peribronchiolar granuloma-associated lymphoid tissue and B-cell gene expression pathways identify asymptomatic Mycobacterium tuberculosis lung infection in Diversity Outbred mice

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL32068
134 Samples

Download data: CEL

Series

Accession:: GSE266564

ID:: 200266564

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2002665622.

Perivascular and peribronchiolar granuloma-associated lymphoid tissue and B-cell gene expression pathways identify asymptomatic Mycobacterium tuberculosis lung infection in Diversity Outbred mice (dataset 1)

(Submitter supplied) Humans are highly genetically diverse, and most are resistant to Mycobacterium tuberculosis. However, lung tissue from genetically resistant humans is not readily available to identify potential mechanisms of resistance. To address this, we model M. tuberculosis infection in Diversity Outbred mice. Like humans, Diversity Outbred mice also exhibit genetically determined susceptibility to M. tuberculosis infection: Progressors who succumb within 60 days of a low dose aerosol infection due to acute necrotizing granulomas, and Controllers who maintain asymptomatic infection for at least 60 days, and then develop chronic pulmonary TB with occasional necrosis and cavitation, over months to greater than 1 year. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL32068
46 Samples

Download data: CEL

Series

Accession:: GSE266562

ID:: 200266562

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000320683.

[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [mogene20st_Mm_ENTREZG_24.0.0]

(Submitter supplied) This Platform is identical to GPL16570 but a custom CDF environment was used to extract data [Brainarray Version 24, mogene20st_Mm_ENTREZG]. Protocol: See manufacturer's web site.