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Items: 3

1.

miRNA-mediated gene silencing in Drosophila larval development involves GW182-dependent and independent mechanisms

(Submitter supplied) microRNAs (miRNAs) regulate a wide variety of biological processes by silencing their target genes. Argonaute (AGO) proteins load miRNAs to form RNA-induced silencing complex (RISC), which mediates translational repression and/or mRNA decay of the targets. A scaffold protein called GW182 directly binds AGO and the CCR4-NOT deadenylase complex, initiating the mRNA decay reaction. Although previous studies have demonstrated the critical role of GW182 in vitro and in cultured cells, its biological significance in living organisms remains largely unexplored. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32218
6 Samples
Download data: RESULTS, TABULAR
Series
Accession:
GSE267756
ID:
200267756

2.

DNBSEQ-G400 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
10 Series
74 Samples
Download data
Platform
Accession:
GPL32218
ID:
100032218

3.

gw null-2 -/+ rep.2

Organism:
Drosophila melanogaster
Source name:
Whole body of first instar larvae
Platform:
GPL32218
Series:
GSE267756
Download data: RESULTS, TABULAR
Sample
Accession:
GSM8275209
ID:
308275209

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