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Items: 4

1.

STAG2 Mutations Reshape the Cohesin-Structured Spatial Chromatin Architecture to Drive Gene Regulation in Acute myeloid Leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other
Platforms:
GPL24676 GPL21697 GPL30173
541 Samples
Download data: BIGWIG, MTX, TSV, TXT
Series
Accession:
GSE268035
ID:
200268035
2.

STAG2 Mutations Reshape the Cohesin-Structured Spatial Chromatin Architecture to Drive Gene Regulation in Acute myeloid Leukemia [ChIP-Seq]

(Submitter supplied) Cohesin shapes the chromatin architecture, including enhancer-promoter interactions. Its components, especially STAG2 but not its paralogue STAG1, are frequently mutated in myeloid malignancies. To elucidate the underlying mechanisms of leukemogenesis, we comprehensively characterized genetic, epigenetic, transcriptional, and chromatin conformational changes in acute myeloid leukemia (AML) patient samples. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21697
299 Samples
Download data: BIGWIG, TXT
Series
Accession:
GSE268031
ID:
200268031
3.

NextSeq 550 (Homo sapiens)

Platform
Accession:
GPL21697
ID:
100021697
4.

ChIP_CD34_27_4_siCtrl_RAD21

Organism:
Homo sapiens
Source name:
cord blood
Platform:
GPL21697
Series:
GSE268031 GSE268035
Download data: BIGWIG
Sample
Accession:
GSM8284212
ID:
308284212

Supplemental Content

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