GSM8288257[Accession] - GEO DataSets

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Items: 4

Select item 2002682281.

Enhancer-promoter hubs organize transcriptional networks promoting oncogenesis and drug resistance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL21697 GPL24676 GPL11154
18 Samples

Download data: BW, COUNTS, HIC

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Accession:: GSE268228

ID:: 200268228

PubMed Full text in PMC Similar studies

Select item 2002682262.

Enhancer-promoter hubs organize transcriptional networks promoting oncogenesis and drug resistance (HiC)

(Submitter supplied) Recent advances in high-resolution mapping of spatial interactions among regulatory elements support the existence of complex topological assemblies of enhancers and promoters known as enhancer-promoter hubs or cliques. Yet, organization principles of these multi-interacting enhancer-promoter hubs and their potential role in regulating gene expression in cancer remains unclear. Here, we systematically identified enhancer-promoter hubs in breast cancer, lymphoma, and leukemia. more...