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Items: 3

1.

Repurposed nuclear speckle and mitosis components induce CTCF clustering to sustain the senescence splicing program [eCLIP]

(Submitter supplied) Senescence —the end-point of the replicative life span of normal cells— is characterized by a complex sequence of molecular and biochemical events. One of these is the dramatic reorganization of CTCF into large senescence-induced CTCF clusters (SICCs). However, the molecular determinants, genomic consequences, and functional purpose of SICCs remained unknown. Here, we combine super-resolution imaging, 3D genomics, and functional assays with computational modelling to address all aspects of SICC emergence. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL21290
8 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE269857
ID:
200269857
2.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
3.

IMR90, ICM, replicate 1, eclip

Organism:
Homo sapiens
Source name:
IMR90
Platform:
GPL21290
Series:
GSE269857
Download data: BW, NARROWPEAK
Sample
Accession:
GSM8328999
ID:
308328999
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db=gds|term=GSM8328999[Accession]|query=3|qty=2|blobid=MCID_672ebc1b530066700064b3e6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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