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Items: 3

1.

Hepatic insulin resistance promotes fructose-enriched diet-induced fatty liver diseases.

(Submitter supplied) Understanding mechanisms causing MAFLD (Metabolic Associated Fatty Liver Disease) and its progression to MASH (metabolic dysfunction-associated steatohepatitis) is clinically important and scientifically challenging. Hepatic insulin resistance is a common component in the progression of MAFLD in patients and experimental animals; however, hepatic steatosis caused by the HFD45% (high-fat diet) decreases during chronic hepatic IR generated by inactivation of Irs1/2 (LDKO), AKT1/2, or InsR 1-3—which is inconsistent with the expected relationship between IR and MAFLD in humans4. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
22 Samples
Download data: XLSX
Series
Accession:
GSE270246
ID:
200270246

2.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
11104 Series
299264 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

3.

IRS1/2-HFD-2

Organism:
Mus musculus
Source name:
Liver
Platform:
GPL17021
Series:
GSE270246
Download data
Sample
Accession:
GSM8338074
ID:
308338074

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db=gds|term=GSM8338074[Accession]|query=1|qty=2|blobid=MCID_6733f0043ec0a11b447fac10|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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