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Items: 3

1.

Proteasome inhibition sensitizes anaplastic Wilms tumor to actinomycin D

(Submitter supplied) Wilms tumor is the most common kidney cancer in children, and anaplastic Wilms tumor is the most chemoresistant histological subtype. Here we explore how anaplastic Wilms tumor cells evade the common chemotherapeutic drug actinomycin D, which inhibits ribosomal biogenesis. We found that, when ribosomal capacity is limited by actinomycin D treatment, anaplastic Wilms tumor cells preferentially translate proteasome components and upregulate proteasome activity. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
36 Samples
Download data: CSV
Series
Accession:
GSE270330
ID:
200270330

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12540 Series
342241 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

WiT49, actD, 2wk, rep1

Organism:
Homo sapiens
Source name:
WiT49
Platform:
GPL18573
Series:
GSE270330
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Sample
Accession:
GSM8339699
ID:
308339699

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db=gds|term=GSM8339699[Accession]|query=7|qty=2|blobid=MCID_6733ef735c1af073747d90e3|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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