GEO DataSets

(Submitter supplied) A dominant-negative gene therapy approach has been proposed and tested on proto-oncogene KRAS, wherein the oncogenic activity (and cell proliferation) of KRAS can be suppressed by introducing a dominant-negative KRAS allele (S17N). We employed REPLACE to conduct continuous evolution on KRAS (S17N) and examined its potential pathways for conferring resistance in this gene therapy methodology.

Organism:

Mesocricetus auratus

Type:

Other

Platform:

GPL29575

12 Samples

Download data: XLSX

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mesocricetus auratus

Type:

Other; Expression profiling by high throughput sequencing

4 related Platforms

112 Samples

Download data: FA, GTF, MTX, TSV, TXT, XLSX