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Items: 3

1.

Effect of abemaiclicb and deletion of TP53 on gene expression in MCF7 cells at different timepoints

(Submitter supplied) CDK4/6 inhibitor, abemaciclib induced cell cycle arrest and senescence in breast cancer. We reported that deletion of TP53 prevented the senescence features. In this study, we knockout TP53 by CRISPR Cas9 system and treated MCF7 cells and p53 knockout cells with abemaciclib for up to 29 days to identify the difference of senescence associated secretary phenotype genes and cell cycle related genes. features.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34281
24 Samples
Download data: TXT
Series
Accession:
GSE272312
ID:
200272312

2.

Illumina NovaSeq X (Homo sapiens)

Organism:
Homo sapiens
48 Series
714 Samples
Download data
Platform
Accession:
GPL34281
ID:
100034281

3.

MCF7 parental, Day 21 rep 1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL34281
Series:
GSE272312
Download data: TXT
Sample
Accession:
GSM8398278
ID:
308398278

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db=gds|term=GSM8398278[Accession]|query=6|qty=2|blobid=MCID_670b3c0bc7d3ca20d584cbc0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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