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Items: 3

1.

Reconstitution of SPO11-dependent double-strand break formation

(Submitter supplied) Homologous meiotic recombination starts with DNA double-strand breaks (DSBs) generated by SPO11 protein. SPO11 is critical for meiosis in most species but the DSBs it makes are also dangerous because of their mutagenic and gametocidal potential, so cells must foster beneficial functions of SPO11 while minimizing its risks. SPO11 mechanism and regulation remain poorly understood. Here we report reconstitution of DNA cleavage in vitro with purified recombinant mouse SPO11 bound to its essential partner TOP6BL. more...
Organism:
Saccharomyces cerevisiae; Escherichia coli; Mus musculus; Cloning vector pUC19
Type:
Other
4 related Platforms
14 Samples
Download data: BED, BW
Series
Accession:
GSE275291
ID:
200275291

2.

NextSeq 1000 (Escherichia coli)

Organism:
Escherichia coli
2 Series
8 Samples
Download data
Platform
Accession:
GPL33919
ID:
100033919

3.

TDP2seq_Ecoli_DNA_SPO11_WT_rep1

Organism:
Escherichia coli
Source name:
Mus musculus, Escherichia coli DNA
Platform:
GPL33919
Series:
GSE275291
Download data: BW
Sample
Accession:
GSM8474252
ID:
308474252

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db=gds|term=GSM8474252[Accession]|query=5|qty=5|blobid=MCID_67389793d9b6b64b3c612344|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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