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Items: 3

1.

Chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin [RNA-seq]

(Submitter supplied) Epigenetic regulation is essential for the normal development of human cerebral cortex, and its disruptions would lead to diverse neurodevelopmental disorders. The epigenetic co-repressor CDYL exhibits widespread expression across various cell clusters within the human embryonic cortex, yet its roles in this intricate process have remained elusive. Here, we show that CDYL is critical for cortical neurogenesis, and CDYL deficiency led to an augmentation in the generation of GABAergic neurons instead of cortical progenitors and neurons in the cortical organoid model. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL34328 GPL34281
18 Samples
Download data: CSV
Series
Accession:
GSE276320
ID:
200276320

2.

Illumina NovaSeq X (Mus musculus)

Organism:
Mus musculus
31 Series
514 Samples
Download data
Platform
Accession:
GPL34328
ID:
100034328

3.

Mouse cortex, KO, E15.5, Rep1

Organism:
Mus musculus
Source name:
Mouse, Cortex, Emx1-Cre; CDYLloxp/loxp
Platform:
GPL34328
Series:
GSE276320
Download data
Sample
Accession:
GSM8496563
ID:
308496563

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db=gds|term=GSM8496563[Accession]|query=8|qty=3|blobid=MCID_670f6c70c7d3ca20d52edbc8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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