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Items: 3

1.

Mechanisms of Pancreatic Acinar Cell Neoplasia Associated with Gene Expression Changes caused by Dietary Exposure of Rats to Ammonium perfluorooctanoate, Wyeth 14,643 or Diethylhexyl phthalate

(Submitter supplied) To identify putative procarcinogenic gene changes associated with pancreatic acinar cell neoplasia in rats exposed to peroxisome proliferator activated receptor alpha agonists, we performed transcription profiling in the pancreas of rats fed diets containing the pancreatic carcinogen Wyeth 14,643 (Wy) at procarcinogenic (50ppm) and non-carcinogenic (20ppm) doses for 1, 7, 28 and 90 days. The effects of these treatments were compared to those of ammonium perfluorooctanoate (APFO) 300 ppm, an agent shown to induce pancreatic acinar cell adenomas in rats, and diethylhexylphthalate (DEHP) 12,000 ppm, an agent not shown to produce pancreatic acinar cell tumors. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL890 GPL2877
109 Samples
Download data: TXT
Series
Accession:
GSE34651
ID:
200034651
2.

Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version)

(Submitter supplied) This microarray contains representative sequences derived from rat RefSeq, high-quality public rat mRNA accessions, homologs to human and mouse RefSeq, EST clusters determined by a leading biopharmaceutical company and the Incyte Zooseq database as well as toxicology markers determined by the National Institute of Environmental Health Sciences (NIEHS) and others. Many of the toxicology markers used in the design of this microarray were released to the public domain for the first time and will be used on this unique microarray product. more...
Organism:
Rattus norvegicus
9 DataSets
30 Series
1 Related Platform
1093 Samples
Download data: TXT
Platform
Accession:
GPL890
ID:
100000890
3.

control vs Wy 20 90day rep 5

Organism:
Rattus norvegicus
Source name:
pancreas, Wy 20ppm treated, 90day (channel 1) pancreas, control, 90day (channel 2)
Platform:
GPL890
Series:
GSE34651
Download data: TXT
Sample
Accession:
GSM852728
ID:
300852728
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Supplemental Content

db=gds|term=GSM852728[Accession]|query=7|qty=2|blobid=MCID_671fd03ee158b40557ccc93f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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