GSM852771[Accession] - GEO DataSets

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Items: 3

Select item 2000346511.

Mechanisms of Pancreatic Acinar Cell Neoplasia Associated with Gene Expression Changes caused by Dietary Exposure of Rats to Ammonium perfluorooctanoate, Wyeth 14,643 or Diethylhexyl phthalate

(Submitter supplied) To identify putative procarcinogenic gene changes associated with pancreatic acinar cell neoplasia in rats exposed to peroxisome proliferator activated receptor alpha agonists, we performed transcription profiling in the pancreas of rats fed diets containing the pancreatic carcinogen Wyeth 14,643 (Wy) at procarcinogenic (50ppm) and non-carcinogenic (20ppm) doses for 1, 7, 28 and 90 days. The effects of these treatments were compared to those of ammonium perfluorooctanoate (APFO) 300 ppm, an agent shown to induce pancreatic acinar cell adenomas in rats, and diethylhexylphthalate (DEHP) 12,000 ppm, an agent not shown to produce pancreatic acinar cell tumors. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platforms:: GPL890 GPL2877
109 Samples

Download data: TXT

Series

Accession:: GSE34651

ID:: 200034651

Analyze with GEO2R

Select item 1000028772.

Agilent-013162 Whole Rat Genome Microarray G4131A (Feature Number version)

(Submitter supplied) With a focus on well known rat genes and homologues to human and mouse genes with useful annotation, Agilent's Whole Rat Genome Oligo Microarray provides researchers with a new tool for modeling human biology in the rat model organism. For researchers, this means they now have access to a microarray made up of relevant content that has been empirically validated by Agilent. Arrays of this design have barcodes that begin with 16013162 or 2513162. more...