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Items: 4

1.

Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
4 related Platforms
67 Samples
Download data: BOWTIE, CEL
Series
Accession:
GSE34996
ID:
200034996

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (RNA-Seq)

(Submitter supplied) Understanding how RNA binding proteins control the splicing code is fundamental to human biology and disease. Here we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alternative pre-mRNA splicing (AS) in human cells. Using splicing-sensitive microarrays, cross-linking and immunoprecipitation coupled with high-throughput sequencing, and cDNA sequencing, we find that more than half of all AS events are regulated by multiple hnRNP proteins, and that some combinations of hnRNP proteins exhibit significant synergy, whereas others act antagonistically. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL9115 GPL11154
31 Samples
Download data: BOWTIE
Series
Accession:
GSE34995
ID:
200034995

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

3.

Illumina Genome Analyzer II (Homo sapiens)

Organism:
Homo sapiens
755 Series
6121 Samples
Download data
Platform
Accession:
GPL9115
ID:
100009115

4.

hnRNPH1 293T RNAseq KD1a

Organism:
Homo sapiens
Source name:
human 293T cells
Platform:
GPL9115
Series:
GSE34995 GSE34996
Download data: BOWTIE
Sample
Accession:
GSM860014
ID:
300860014

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