GSM896278[Accession] - GEO DataSets

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Items: 4

Select item 2000365331.

Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in uninfected, resolved and chronically infected woodchucks

(Submitter supplied) The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in humans, but the lack of sequence information has hitherto precluded functional genomics analysis. To address this major limitation of the model, we report here the sequencing, assembly and annotation of the woodchuck transcriptome, together with the generation of custom woodchuck microarrays. more...

Organism:: Marmota monax

Type:: Expression profiling by array

Platform:: GPL15354
123 Samples

Download data: PAIR

Series

Accession:: GSE36533

ID:: 200036533

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000362502.

Transcriptomic analysis of the woodchuck model of chronic hepatitis B

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Marmota monax

Type:: Expression profiling by array

Platform:: GPL15354
291 Samples

Download data: PAIR

Series

Accession:: GSE36250

ID:: 200036250

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000153543.

NimbleGen Woodchuck Gene Expression HX3 Microarray

(Submitter supplied) After filtering the probe sets by a BLASTN E-value <1e-5 and compression by HomoloGene symbol, 13,448 human homologs were represented on the custom chip. In addition, probe sets which detect WHV polymerase (nt. 258-1750), mature WHsAg (nt. 296-920), WHsAg signal peptide (nt. 2992-3226), WHx (nt. 1503-1887) and WHcAg (nt. 2077-2587) of the WHV7-11 (NC_004107.1) sequence were also included on the chip. more...