GSM936502[Accession] - GEO DataSets

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Items: 4

Select item 2000381991.

Induction of hepatocellular carcinoma through activation of stromal cells in Pdgf-c transgenic mice

(Submitter supplied) Liver cirrhosis is a strong risk factor for the development of hepatocellular carcinoma (HCC), yet the mechanisms by which cirrhosis predisposes patients to tumorigenesis are not well understood. Transgenic mice expressing platelet-derived growth factor C (Pdgf-c) under the control of the albumin promoter provide a unique animal model that mimics the step-wise disease progression in humans from fibrosis to HCC. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5320
Platform:: GPL6246
16 Samples

Download data: CEL

Series

Accession:: GSE38199

ID:: 200038199

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53202.

Platelet-derived growth factor C transgenic model of hepatocellular carcinoma: liver stromal cells

Analysis of liver stroma from 8.8-week-old PDGF-C transgenics wherein PDGF-C is ectopically expressed in hepatocytes. The transgenics develop progressive liver fibrosis with a high incidence of HCC. Results provide insight into PDGF-C-driven molecular changes in liver stroma contributing to HCC.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL6246
Series:: GSE38199
16 Samples

Download data: CEL

DataSet

Accession:: GDS5320

ID:: 5320

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000062463.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site