GEO DataSets

(Submitter supplied) We report the application of the Illumina/Solexa sequencing-by-synthesis platform to analysis differential expression genes of two key tissues (brain and adipose tissue) during hibernation vs. aroused state, with a hibernating bat species (Myotis ricketti) as model. Total of 12272 genes were identified including 11291 genes in brain and 10691 genes in adipose tissue. Chi-square test indicated that 1943 and 3673 genes in brain and adipose tissues respectively reached the significant level (P ≤ 0.01), including 1243 up-regulated and 700 down-regulated genes in hibernating brain and 2621 up-regulated and 1052 down-regulated genes in hibernating adipose tissue. more...

Organism:

Myotis ricketti

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18718

6 Samples

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(Submitter supplied) We report the application of the Illumina/Solexa sequencing-by-synthesis platform to identify microRNA, which invovled in bat hibernating regualtion, in brain and adipose tissue. Total 866 microRNAs (including 477 novels) were identified and 269 microRNAs showed significant expression differences during hibernation, including 183 in brain and 199 in adipose tissue. Expressed pattern analysis indicated that two-thirds of differential expressed microRNAs showed down-regulated during hibernation in both tissues. more...

Organism:

Myotis ricketti

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL13491

4 Samples

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(Submitter supplied) As the only truly flying mammals, bats use their unique wing formed from elongated digits connected by membranes to power their flight. The forelimb of bats consists of four elongated digits (digits II-V) and one shorter digit (digit I) that is morphologically similar to the hindlimb digits. Elongation of bat forelimb digits is thought to results from changes in the temporal and spatial expression of a number of developmental genes. more...

Organism:

Myotis ricketti

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15028

3 Samples

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