GEO DataSets

(Submitter supplied) The goal of this analysis is to define the aerobic and anaerobic regulons for the transcription factor Mlc (Makes Large Colonies) in the periodontal pathogen Aggregatibacter actinomycetemcomitans. The objectives were met by comparing the mRNA profile of a wild type strain, JP2, to that of an isogenic mutant deleted of the Mlc gene. Both strains were grown aerobically and anaerobically. The results show that Mlc is involved in the regulation of dozens of genes in both growth conditions.

Organism:

Aggregatibacter actinomycetemcomitans; Aggregatibacter actinomycetemcomitans HK1651

Type:

Expression profiling by array

Platform:

GPL11227

16 Samples

Download data: PAIR

(Submitter supplied) Investigation of whole genome gene expression levels of P. gingivalis W83, F. nucleatum DSMZ 25586, S. sanguinis SK36, A. actinomycetemcomitans HK1651, S. mutans UA159 in an 24 h old culture. Additionally, whole genome gene expression level changes of S. mutans UA159 biofilm cells after co-cultivation with S. mitis ATCC 11843 were compared to its single species biofilm growth after 24 h. Aim: Demonstration of the usefulness of a five-species gene expression array. more...

Organism:

Fusobacterium nucleatum; Aggregatibacter actinomycetemcomitans HK1651; Streptococcus mutans UA159; Porphyromonas gingivalis W83; Streptococcus mitis; Streptococcus sanguinis SK36

Type:

Expression profiling by array

Platforms:

GPL13444 GPL10873

12 Samples

Download data: CALLS, PAIR, TXT

(Submitter supplied) The goal of this analysis is to define the anaerobic regulon for the global transcription factor CRP (catabolite repressor protein) in the periodontal pathogen Aggregatibacter actinomycetemcomitans. The objectives were met by comparing the mRNA profile of a wild type strain, JP2, to that of an isogenic mutant deleted of the CRP gene. Both strains were grown anaerobically.

Organism:

Aggregatibacter actinomycetemcomitans; Aggregatibacter actinomycetemcomitans HK1651

Type:

Expression profiling by array

Platform:

GPL11227

6 Samples

Download data: PAIR

(Submitter supplied) 385K-format: 3 replicates of up to 13 probes per gene, 60-mer oligonucleotides, 3510 randomized sequence probes. The array includes probes for Porphyromonas gingivalis W83, Fusobacterium nucleatum DSMZ 25586, Streptococcus sanguinis SK36, Actinobacillus actinomycetemcomitans HK1651, and Streptococcus mutans UA159. A condensed version of this platform is assigned accession number GPL10873. Alternative version of this Platform including probes only for Streptococcus sanguinis SK36 is assigned accession number GPL15399. more...

Organism:

Fusobacterium nucleatum; Streptococcus mutans UA159; Porphyromonas gingivalis W83; Aggregatibacter actinomycetemcomitans HK1651; Streptococcus sanguinis SK36

1 Series

2 Related Platforms

6 Samples

Download data: NDF, NGD

(Submitter supplied) NimbleGen design name 080902_Aact_DK_EXP, NimbleGen design ID 8151. An expression array for 2,116 genes from A. actinomycetemcomitans strain HK1651. There are 11 different 60-mer probes /gene for 94% of the genes, and the entire probe set (22,537 probes) is replicated (technical replicates) three times on each array. Each probe set is contained on a quarter of a chip and there are also 4,426 random probes per array. more...

Organism:

Aggregatibacter actinomycetemcomitans HK1651

2 Series

22 Samples

Download data: NDF, NGD