GEO DataSets

(Submitter supplied) This study represents the first in vivo genome wide analysis of gene epxression of Group A Streptococcus (GAS) in humans with pharyngitis. The micorarray used is a custom microarray that relies on an electrochemical reaction as the measured signal rather than flourescence. Distinct clusters of gene expression were discovered and analyzed. A functional analysis examining differences and similarities between the clusters was performed.

Organism:

Streptococcus pyogenes MGAS9429; Streptococcus pyogenes MGAS315; Streptococcus pyogenes M1 GAS; Streptococcus pyogenes MGAS6180; Streptococcus pyogenes MGAS2096; Homo sapiens; Streptococcus pyogenes SSI-1; Streptococcus pyogenes MGAS5005; Streptococcus pyogenes MGAS10750

Type:

Expression profiling by array

Platform:

GPL10562

14 Samples

Download data: TXT

(Submitter supplied) Emerging known and unknown pathogens create profound threats to public health. Platforms for rapid detection and characterization of microbial agents are critically needed to prevent and respond to disease outbreaks. Available detection technologies cannot provide broad functional information about known and novel organisms. As a step toward developing such a system, we have produced and tested a series of high-density functional gene arrays to detect elements of virulence and antibiotic resistance mechanisms. more...

Organism:

Staphylococcus aureus subsp. aureus Mu50; Escherichia coli CFT073; Streptococcus pyogenes MGAS5005; Staphylococcus aureus; Escherichia coli O157:H7 str. EDL933; Enterococcus faecalis V583; Staphylococcus saprophyticus; Escherichia coli str. K-12 substr. MG1655; Salmonella enterica; unidentified

Type:

Other

Platform:

GPL6656

12 Samples

Download data: PAIR

(Submitter supplied) The full array layout file provided as a supplementary file. Protocol: Probe sets were 30-40mers in length, sense strand and were selected using a Combimatrix probe selection algorithm taking into account gene (>90% BLAST score) and serotype specificity, Tm, hairpins and GC content. Arrays were constructed using the CustomArray Synthesizer at Combimatrix. CustomArray uses a specially modified CMOS semiconductor to direct the molecular assembly of a specific sequence of DNA bases in response to a digital command. more...

Organism:

Streptococcus pyogenes M1 GAS; Streptococcus pyogenes SSI-1; Streptococcus pyogenes MGAS315; Streptococcus pyogenes MGAS5005; Streptococcus pyogenes MGAS6180; Streptococcus pyogenes MGAS9429; Streptococcus pyogenes MGAS2096; Streptococcus pyogenes MGAS10750

1 Series

14 Samples

Download data: TXT