GEO DataSets

(Submitter supplied) The mechanisms by which viruses hijack their host’s genetic machinery are of current interest. When bacteriophage T4 infects Escherichia coli, three different ARTs (ADP-ribosyltransferases) reprogram the host’s transcriptional and translational apparatus through ADP-ribosylation using nicotinamide adenine dinucleotide (NAD) as substrate. Recently, NAD was identified as a 5’-modification of cellular RNAs. more...

Organism:

Escherichia coli B

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32701

11 Samples

Download data: TXT

(Submitter supplied) Bacteriophages are highly abundant viruses of bacteria. The major role of phages in shaping bacterial communities and their emerging medical potential as antibacterial agents has trig-gered a rebirth of phage research. To understand the molecular mechanisms by which phages hijack their host, omics technologies can provide novel insights into the organization of tran-scriptional and translational events occurring during the infection process. more...

Organism:

Escherichia coli B

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32563

15 Samples

Download data: TXT

(Submitter supplied) Here we report on an RNAseq method in combination with spike-in cells to measure global changes in the transcription pattern after valine-induced isoleucine starvation of a standard E. coli K12 strain. Due to the spike-in method we were able to show that ribosomal RNA is degraded during isoleucine starvation and we showed how this change in cellular RNA content affect the estimated regulation of mRNA levels compared to if spike-in were not utilized. more...

Organism:

Escherichia coli K-12; Escherichia coli B

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27414

12 Samples

Download data: FASTA, GFF3, TXT

(Submitter supplied) Microarrays have become a powerful tool for DNA-based molecular diagnostics and identification of pathogens. However, most of them target a limited range of organisms and are generally based on only one or very few genes for organism identification. Although such microarrays are proven tools for species identification, they suffer from the fact that identification is only possible for organisms for which probes were specifically pre-developed. more...

Organism:

Escherichia coli K-12; Micrococcus luteus; Pantoea agglomerans; Escherichia coli B; synthetic construct; Pantoea stewartii; Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Type:

Genome variation profiling by array

Platform:

GPL8295

23 Samples

Download data: PAIR