GEO DataSets

(Submitter supplied) Chromatin is composed of DNA wrapped around nucleosomes, complexes consisting of highly basic proteins called histones. Histone variants are non-canonical variants of histones that have specific functions. The Apicomplexan parasite Toxoplasma gondii possesses conserved histone variants CenH3, H3.3, H2A.Z, H2A.X, as well as the parasite-specific H2B variant, H2BV (or H2B.Z). We surveyed the genome-wide distribution of T. more...

Organism:

Toxoplasma gondii ME49; Toxoplasma gondii RH

Type:

Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL15564 GPL15563

10 Samples

Download data: GFF, PAIR, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Toxoplasma gondii; Toxoplasma gondii ME49

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL23377 GPL13740

12 Samples

Download data: TXT

(Submitter supplied) Toxoplasma gondii is a unicellular eukaryote belonging to the Apicomplexa phylum. It is an obligate intracellular parasite of critical importance to primarily infected pregnant women and immunosuppressed patient. ApiAP2 are a family of conserved transcription factors (TF) that play an important role in regulating gene expression in apicomplexan parasites. Previous studies had revealed the ability of one of these TFs, TgAP2XI-5, to bind to transcriptionally active promoters of genes expressed during the S/M phase such as rhoptry and micronemes genes. more...

Organism:

Toxoplasma gondii; Toxoplasma gondii ME49

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL13740

6 Samples

Download data: TXT

(Submitter supplied) Apicomplexa are intracellular parasites that cause human and animal disease. They proliferate by a unique mechanism that combines closed mitosis with daughter cell budding. In past work we demonstrated that the Toxoplasma gondii centromeres are sequestered to the nuclear periphery proximal to the centrosome throughout the cell cycle. Here we show that interphase centromere clustering is not mediated by the mitotic spindle. more...

Organism:

Toxoplasma gondii; Toxoplasma gondii ME49

Type:

Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL15563 GPL15564

6 Samples

Download data: GFF, PAIR

(Submitter supplied) Plasmodium and Toxoplasma are parasites of major medical importance that belong to the Apicomplexa phylum of protozoa. These parasites transform into various stages during their life cycle and express a specific set of proteins at each stage. Although still little is known of how gene expression is controlled in Apicomplexa, histone modifications, particularly acetylation, are emerging as key regulators of parasite differentiation and stage conversion. more...

Organism:

Toxoplasma gondii ME49; Toxoplasma gondii

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL8305

2 Samples

Download data: PAIR

(Submitter supplied) Based on genome build ToxoDB 6.4 (http://toxodb.org/toxo/). Protocol: See manufacturer's web site at http://www.agilent.com/.

Organism:

Toxoplasma gondii ME49

2 Series

6 Samples

Download data

(Submitter supplied) Tiling microarray encompassing 63 Mb of Toxoplasma gondii genome (reference genome strain ME49; chromosomes Ia, Ib, II, III, IV, V, VI, VIIa, VIIb, VIII, IX, X, XI and XII, and unmapped contigs). The genome wide chip was designed using the Nimblegen isothermal protocol design based upon Release 4.1 of the T. gondii ME49 genome (www.toxodb.org). The "target Tm" for all probes is 76 C. There are 392,074 probes total on each array for a total of 784,148 probes, including controls. more...

Organism:

Toxoplasma gondii ME49

2 Series

8 Samples

Download data: NDF, POS

(Submitter supplied) Tiling microarray encompassing 63 Mb of Toxoplasma gondii genome (reference genome strain ME49; chromosomes Ia, Ib, II, III, IV, V, VI, VIIa, VIIb, VIII, IX, X, XI and XII, and unmapped contigs). The genome wide chip was designed using the Nimblegen isothermal protocol design based upon Release 4.1 of the T. gondii ME49 genome (www.toxodb.org). The "target Tm" for all probes is 76 C. There are 392,074 probes total on each array for a total of 784,148 probes, including controls. more...

Organism:

Toxoplasma gondii ME49

2 Series

8 Samples

Download data: NDF, POS

(Submitter supplied) Tiling microarray encompassing 65 Mb of Toxoplasma gondii (strain ME49) genome (chromosomes Ia, Ib, II, III, IV, V, VIIa, VIIb, VIII, IX, X, XI and XII). RefSeq genome accession: NZ_ABPA00000000.1. 50mer probes selected at 82 bp interval spacing From : TOXODB release 4.0 Genomic sequence available at: http://toxodb.org/common/downloads/release-4.0/ Native NimbleGen files (ndf, pos) are linked below as supplementary files. more...

Organism:

Toxoplasma gondii ME49

1 Series

2 Samples

Download data: NDF, POS, TXT