GEO DataSets

(Submitter supplied) Ferric uptake regulator (Fur) is the major regulator of iron acquisition in Escherichia coli and other bacteria. In the present study, the role of Fur in anaerobic S. enterica serovar Typhimurium was determined by transcriptome analysis, reporter assays, and enzymatic assays. In anaerobic Δfur, 298 genes were differentially expressed. In general, Fur repressed genes required for iron acquisition/storage, metabolism, electron transport, oxidative/nitrosative stress, and modulators of virulence. more...

Organism:

Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella

Type:

Expression profiling by array

Platform:

GPL1835

6 Samples

Download data: CSV

(Submitter supplied) Background: Salmonella enterica serovar Typhimurium (S. Typhimurium) is a Gram-negative pathogen that must successfully adapt to the broad fluctuations in the concentration of dissolved dioxygen encountered in the host. In Escherichia coli, ArcA (Aerobic Respiratory Control) helps the cells to sense and respond to the presence of dioxygen. The global role of ArcA in E. coli is well characterized; however, little is known about its role in anaerobically grown S. more...

Organism:

Salmonella; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Expression profiling by array

Platform:

GPL1835

6 Samples

Download data: TXT

(Submitter supplied) Salmonella typhimurium 14028s Transposon library recovered from spleen after IP passage of 2x10^6 through BALB/c mouse, compared to the initial Transposon library grown in LB broth (kanamycin 50ug/ml), O/N at 37°C with aeration Keywords: Transposon tag analysis

Organism:

Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella

Type:

Genome variation profiling by array

Platform:

GPL1835

21 Samples

Download data

(Submitter supplied) Salmonella typhimurium 14028s Transposon library grown in M9 minimal medium (arabinose 0.4%), O/N at 37°C with aeration, compared to the initial library selected on Luria agar plates + kanamycin (50ug/ml), O/N at 37°C Keywords: Transposon tag analysis

Organism:

Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella

Type:

Genome variation profiling by array

Platform:

GPL1835

9 Samples

Download data

(Submitter supplied) We have exploited a spontaneously isolated mutant IgaA(T191P) that is near-maximally activated for the Rcs system, to identify a vast set of genes that respond, and report new regulatory properties of this signaling system in Salmonella enterica serovar Typhimurium. Microarray data show that the Rcs system normally functions as a positive regulator of SPI-2 and other genes important for growth of Salmonella in macrophages, although when highly activated, the system completely represses the SPI-1/SPI-2 virulence, flagellar, and fimbrial biogenesis pathways. more...

Organism:

Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella enterica; Salmonella

Type:

Expression profiling by array

Platforms:

GPL1835 GPL4804 GPL3788

30 Samples

Download data

(Submitter supplied) Reactive nitrogen species (RNS) derived from dietary and salivary inorganic nitrates (NO3-) foment innate host defenses associated with the acidity of the stomach. The mechanisms by which these reactive species exert antibiotic activity in the gastric lumen are, however, poorly understood. To identify targets of RNS, the genetically tractable acid tolerance response (ATR) that enables enteropathogens to survive the harsh acidity of the stomach was screened for signaling pathways responsive to RNS. more...

Organism:

Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella

Type:

Expression profiling by array

Platform:

GPL1835

3 Samples

Download data: TXT

(Submitter supplied) Salmonella enterica var. Typhimurium (S. Typhimurium) is a Gram-negative, facultative intracellular pathogen that infects the intestinal tracts of humans and animals. In the host, S. Typhimurium encounters a wide range of oxygen concentrations going from oxic conditions in the stomach to near anoxic conditions in the distal sigmoid colon-rectal junction. In Escherichia coli, FNR (Fumarate Nitrate Reductase) is one of the main regulatory proteins involved in oxygen sensing and in controlling the transcription of the genes required for the aerobic/anaerobic transition.. more...

Organism:

Salmonella; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Expression profiling by array

Platform:

GPL1835

6 Samples

Download data

(Submitter supplied) Transcriptome analysis of two independently derived hns mutants compared to an isogenic wild-type Salmonella (strain 14028s - lab ID# WN153). Note: both the wild-type and hns strains carry an additional mutation in the rpoS locus (encoding the stationary phase sigma factor) resulting in a deletion of amino acids 61-65 that diminish its activity. Keywords: cell type comparison

Organism:

Salmonella; Salmonella enterica; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Expression profiling by array

Platforms:

GPL1305 GPL1835

24 Samples

Download data

(Submitter supplied) The NimbleGen array contains 387,000 46~50-mer oligos, including 377,230 salmonella probes whose sequences only hit genome once. The probes were designed based on Salmonella typhimurium LT2 (NC_003197) genome, with a moving window of about 12 bases. Raw intensities were normalized by the median intensity in each channel and the ratios were calculated by log base 2 (hns-bound DNA / genomic DNA) after the normalization. more...

Organism:

Salmonella

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL3786

2 Samples

Download data

(Submitter supplied) Gene expression measured at maximal Salmonella growth rate in different media Keywords: other

Organism:

Salmonella; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Expression profiling by array

Platform:

GPL1835

96 Samples

Download data

(Submitter supplied) Global expression profiles of Salmonella typhi grown in the supernatant of infection and within human macrophages at 0h, 2h, 8h and 24h were obtained. Stringent analytical methods were used to compare Salmonella typhi cDNAs and revealed that known virulence factors, such as the SPI-1 and SPI-2 encoded type III secretion systems, were found to be expressed as predicted during infection by Salmonella. more...

Organism:

Salmonella enterica; Salmonella; Salmonella enterica subsp. enterica serovar Typhi

Type:

Expression profiling by array

Platforms:

GPL1835 GPL548

30 Samples

Download data

(Submitter supplied) Transcription profiles of Typhimurium 14028 wt versus 14028 cheA, cheB, cheZ, flgM and flgM/cheY mutants at 3h on agar plates Keywords: other

Organism:

Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella; Salmonella enterica

Type:

Expression profiling by array

Platforms:

GPL1835 GPL548

30 Samples

Download data

(Submitter supplied) Comparative genomic hybridization of a temporally and locally diverse set of S. enterica ssp I serovar Enteritidis isolates, and some closely related serovar Dublin and Gallinarum strains, to the sequenced Enteritidis PT4 Keywords: other

Organism:

Salmonella; Salmonella enterica; Salmonella enterica subsp. enterica

Type:

Genome variation profiling by array

Platforms:

GPL548 GPL1305 GPL1835

111 Samples

Download data

(Submitter supplied) WT 14028 versus mutant Keywords: other

Organism:

Salmonella; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Expression profiling by array

Platform:

GPL1835

12 Samples

Download data

(Submitter supplied) in situ oligonucleotide

Organism:

Salmonella

Download data: NCD, NDF, NGD

(Submitter supplied) Salmonella spp. sequences spotted on the array. Corynebacterium phage BFK20 sequences included as controls. The data table reflects the condensed representation of the Platform. The complete array layout file representing the quadruplicate-spotted features is linked as a supplementary file. Protocol: Dried HPLC-purified oligonucleotides were resuspended in 1x Micro Spotting Solution Plus (ArrayIt) and spotted in duplicates on the SuperEpoxy slides (ArrayIt). more...

Organism:

Salmonella

Download data: TXT

(Submitter supplied) This set includes 382864 46~50mer oligonucleotides, mostly 50-mers. The probes were designed based on Salmonella typhimurium LT2 (NC_003197.1) genome, with a moving window of about 12 bases. Protocol: in situ oligonucleotide

Organism:

Salmonella

1 Series

2 Samples

Download data

(Submitter supplied) Custom made Salmonella array

Organism:

Salmonella

13 Series

264 Samples

Download data