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Items: 1 to 20 of 30

1.

STING mediates immune responses in a unicellular choanoflagellate

(Submitter supplied) To reconstruct the ancestry of animal innate immunity, we have developed the choanoflagellate Monosiga brevicollis, one of the closest living relatives of animals, as a model for studying mechanisms underlying pathogen recognition and immune response. We found that M. brevicollis is killed by exposure to Pseudomonas aeruginosa bacteria and selectively avoids ingesting them. Moreover, M. brevicollis expresses STING, which, in animals, activates innate immune pathways in response to cyclic dinucleotides during pathogen sensing. more...
Organism:
Monosiga brevicollis
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL30126 GPL30125
24 Samples
Download data: TAB
Series
Accession:
GSE174340
ID:
200174340
2.

The Early Origins and Evolution of microRNAs and piRNAs in Animals

(Submitter supplied) We explored the potential for small RNA biology in organisms that diverged basal to Bilateria, identifying both miRNAs and piRNAs in Nematsotella and Amphimedon
Organism:
Nematostella vectensis; Monosiga brevicollis; Amphimedon queenslandica; Trichoplax adhaerens
Type:
Non-coding RNA profiling by high throughput sequencing
4 related Platforms
17 Samples
Download data: TXT
Series
Accession:
GSE12578
ID:
200012578
3.

Illumina NovaSeq 6000 (Monosiga brevicollis)

Organism:
Monosiga brevicollis
1 Series
4 Samples
Download data
Platform
Accession:
GPL30126
ID:
100030126
4.

Illumina NextSeq 500 (Monosiga brevicollis)

Organism:
Monosiga brevicollis
1 Series
20 Samples
Download data
Platform
Accession:
GPL30125
ID:
100030125
5.

Illumina Genome Analyzer (Monosiga brevicollis)

Organism:
Monosiga brevicollis
1 Series
1 Sample
Download data
Platform
Accession:
GPL9306
ID:
100009306
6.

STING2d12-2prime3primecgamp-2

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30126
Series:
GSE174340
Download data
Sample
Accession:
GSM5292368
ID:
305292368
7.

STING2d12-2prime3primecgamp-1

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30126
Series:
GSE174340
Download data
Sample
Accession:
GSM5292367
ID:
305292367
8.

STING2d12_control_2

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30126
Series:
GSE174340
Download data
Sample
Accession:
GSM5292366
ID:
305292366
9.

STING2d12_control_1

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30126
Series:
GSE174340
Download data
Sample
Accession:
GSM5292365
ID:
305292365
10.

Mbre_control2

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292364
ID:
305292364
11.

Mbre_control1

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292363
ID:
305292363
12.

3prime3prime-cGAMP-B

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292362
ID:
305292362
13.

3prime3prime-cGAMP-A

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292361
ID:
305292361
14.

Mbre_cGamp2

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292360
ID:
305292360
15.

Mbre_cGamp1

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292359
ID:
305292359
16.

MB_h20_3

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292358
ID:
305292358
17.

MB_cGAMP_3

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292357
ID:
305292357
18.

Control4

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292356
ID:
305292356
19.

Control3

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292355
ID:
305292355
20.

Control2

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
Download data
Sample
Accession:
GSM5292354
ID:
305292354
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Supplemental Content

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