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Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates (LAM63 IgG)

(Submitter supplied) Increasing evidence supports a role ofthat antibodies in thecan defense protect against active tuberculosis (TB) but knowledge of potentially protective antigens, especially at in the mucosal airways level, is limited. The main objective of this study was to identify antigen-specific airway and systemic immunoglobulin isotype responses that were associated with the outcome of controlled latent Mycobacterium tuberculosis (Mtb) infection (LTBI) compared to uncontrolled infection (TB) in nonhuman primates. more...
Organism:
Macaca fascicularis; synthetic construct
Type:
Protein profiling by protein array
Platform:
GPL30414
270 Samples
Download data: XLSX
Series
Accession:
GSE243659
ID:
200243659

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