Phase 1 trial of durvalumab (anti-PD-L1) in combination with lenalidomide in relapsed/refractory cutaneous T cell lymphoma - - GEO DataSets - NCBI

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Phase 1 trial of durvalumab (anti-PD-L1) in combination with lenalidomide in relapsed/refractory cutaneous T cell lymphoma

(Submitter supplied) T cells in cutaneous T-cell lymphoma (CTCL) are functionally exhausted, expressing immune inhibitory molecules such as PD1 and PD-L1. Durvalumab selectively targets PD-L1 on exhausted T cells and distinct cells within the CTCL tumor microenvironment (TME) and may restore an anti-tumor immune response. The oral immunomodulator lenalidomide, which has shown activity in CTCL, may enhance immune checkpoint blockade by durvalumab. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
24 Samples

Download data: TXT

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Accession:: GSE271668

ID:: 200271668

Analyze with GEO2R

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Phase 1 trial of durvalumab (anti-PD-L1) in combination with lenalidomide in rel...
Phase 1 trial of durvalumab (anti-PD-L1) in combination with lenalidomide in relapsed/refractory cutaneous T cell lymphoma
Accession: GSE271668

GEO DataSets
GEO DataSet Links for BioProject (Select 1132888) (1)
GEO DataSets
Homo sapiens G protein-coupled receptor 161 (GPR161), transcript variant 15, mRN...
Homo sapiens G protein-coupled receptor 161 (GPR161), transcript variant 15, mRNA
gi|1833303429|ref|NM_001381909.1|

Nucleotide
Homo sapiens thioredoxin 2 (TXN2), mRNA; nuclear gene for mitochondrial product
Homo sapiens thioredoxin 2 (TXN2), mRNA; nuclear gene for mitochondrial product
gi|1519499539|ref|NM_012473.4|

Nucleotide
Taxonomy Links for Protein (Select 290790050) (1)
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