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Transcriptional memory drives accelerated re-activation of secondary metabolite production in Aspergillus nidulans [ChIP-seq]

(Submitter supplied) Organisms are repeatedly exposed to fluctuating environmental and nutritional conditions. Transcriptional memory has been shown to be a mechanism to cope with these fluctuations because it increases the speed and the magnitude of the cellular response to a certain re-occurring condition and therefore optimizes adaptation and fitness in a given environment. We found that genes coding for sterigmatocystin (ST) production in Aspergillus nidulans are activated stronger when cells are repeatedly exposed to nutrient starvation, compared to cells that experience this condition for the first time. more...
Organism:
Aspergillus nidulans
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL30666
26 Samples
Download data: BW
Series
Accession:
GSE275591
ID:
200275591

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