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Items: 2

1.

SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells

(Submitter supplied) Global expression analysis of neural crest-like skin-derived precursors (SKPs) and Sox2-positive follicle dermal cells that SKPs originate from. In spite of the remarkable regenerative capacity of mammalian skin, an adult dermal stem cell has not yet been identified. Here, we provide evidence that SKPs, multipotent neural crest-like skin-derived precursors, represent an adult dermal stem cell. When transplanted into adult skin, SKPs can reconstitute the adult dermis, contribute to dermal wound-healing, home to a hair follicle niche, and instruct epidermal cells to make hair follicles. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3753
Platform:
GPL6246
9 Samples
Download data: CEL, CHP
Series
Accession:
GSE18690
ID:
200018690

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.
Full record GDS3753

Skin-derived precursors

Analysis of primary passage neonatal skin-derived precursors (SKP) and Sox2-positive hair follicle dermal cells from which SKPs derive. SKPs and Sox2+ dermal precursors share similar function and transcriptional profile. Results provide insight into potential role of SKPs as adult dermal stem cells.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 cell type sets
Platform:
GPL6246
Series:
GSE18690
9 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3753
ID:
3753

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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