GEO DataSet Links for BioProject (Select 140375) - GEO DataSets

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Items: 2

Select item 2000291101.

Fibrogenic and redox-related but not proinflammatory genes are upregulated in lewis rat model of chronic silicosis

(Submitter supplied) Silicosis, a fibrotic granulomatous lung disease, may occur through accidental high-dose or occupational inhalation of silica, leading to acute/accelerated and chronic silicosis, respectively. While chronic silicosis has a long asymptomatic latency, lung inflammation and apoptosis are hallmarks of acute silicosis. In animal models, histiocytic granulomas develop within days after high-dose intratracheal silica instillation. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS4579
Platform:: GPL1355
6 Samples

Download data: CEL

Series

Accession:: GSE29110

ID:: 200029110

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45792.

Subchronic silicosis model: whole lung

Analysis of lung at 28 wk following subchronic silica inhalation exposure to occupationally relevant doses and particle sizes of aerosolized silica. Results provide insight into molecular events associated with chronic silicosis.