GEO DataSets

(Submitter supplied) We used Au nanoparticles (Au-NPs) as a model for studying particle specific effects of manufactured nanomaterials (MNMs) by examining the toxicogenomic responses in a model soil organism, free living nematode Caenorhabditis elegans. Global genome expression for nematodes exposed to 4-nm citrate-coated Au-NPs at the LC10 (5.9 mg L-1) revealed significant differential expression of 797 genes. The levels of expression for five genes (apl-1, dyn-1, act-5, abu-11, and hsp-4) were confirmed independently with qRT-PCR. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array

Dataset:

GDS4571

Platform:

GPL200

6 Samples

Download data: CEL

Analysis of age-synchronized L3 nematodes exposed to LC10 of gold nanoparticles (Au-NPs). The Au-NPs are used as a model for studying particle-specific effects of manufactured nanomaterials (MNMs). Results provide insight into in vivo particle-specific toxicity of Au-NPs to C. elegans.

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL200

Series:

GSE32521

6 Samples

Download data: CEL