GEO DataSet Links for BioProject (Select 216142) - GEO DataSets

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Items: 2

Select item 2000501381.

Lentiviral shRNA knockdown of PTK7 in lung adenocarcinoma cell lines NCI-H1299 and NCI-H2009

(Submitter supplied) PTK7 was identified from a meta-analysis of 1905 non-small-cell lung cancer (NSCLC) samples across 12 datasets to be one of seven genes commonly up-regulated in lung adenocarcinoma (ADC). Using ADC cell lines NCI-H1299 and NCI-H2009, disruption of PTK7 resulted in decreased cell viability and induction of apoptosis. A xenotransplantation model of the cell lines with PTK7 knock-down also resulted in decreased tumor burden. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5391
Platform:: GPL6244
8 Samples

Download data: CEL

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Accession:: GSE50138

ID:: 200050138

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53912.

Protein tyrosine kinase PTK7 knockdown effect on lung adenocarcinoma cell lines

Analysis of lung adenocarcinoma (ADC) cell lines NCI-H1299 and NCI-H2009 depleted for protein tyrosine kinase PTK7 using two independent shRNAs (shPTK7-1 and shPTK7-2). Results provide insight into the role of PTK7 in lung ADCs.