GEO DataSet Links for BioProject (Select 247965) - GEO DataSets

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Items: 3

Select item 2000577281.

Expression data from AsPC1 cells treated with ICG-001

(Submitter supplied) The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression changes in the pancreatic cancer cell line AsPC1 following treatment with ICG-001 or siRNA-mediated knockdown of CTNNB1 (beta-catenin)

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS5323 GDS5324
Platform:: GPL570
16 Samples

Download data: CEL

Series

Accession:: GSE57728

ID:: 200057728

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53242.

Beta-catenin depletion effect on pancreatic cancer cell line

Analysis of AsPc1 pancreatic adenocarcinoma cells depleted for beta-catenin. Dysregulation of Wnt/β-catenin signaling is implicated in the pathogenesis of cancers. Results compared to those from AsPC1 cells treated with the CREB-binding protein inhibitor ICG-001 (GDS5323).

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL570
Series:: GSE57728
4 Samples

Download data: CEL

DataSet

Accession:: GDS5324

ID:: 5324

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 53233.

CREB-Binding Protein Inhibitor ICG-001 effect on pancreatic cancer cell line: time course

Analysis of AsPC1 pancreatic adenocarcinoma (PDAC) cells treated with IGC-001 up to 24 hours. IGC-001 binds to CREB-binding protein to disrupt its interaction with β-catenin. Results compared to β-catenin depletion (GDS5324) and provide insight into the therapeutic potential of IGC-001 in PDAC.