GEO DataSet Links for BioProject (Select 266408) - GEO DataSets

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Items: 2

Select item 2000629991.

Expression data from study on IL33 signaling in Dusp5 deficient eosinophils

(Submitter supplied) Dusp5 regulates ERK phosporylation following IL-33 receptor ligation in cultured eosinophils. Dusp5 deficient eosinophils show increased ERK phosphorylation, and as a result are less apoptotic. Since ERK stimulation results in downstream activation of transcription factors, we are utilizing a microarray approach to find alterations in gene expression to uncover potential mechanisms for increased cell survival.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5468
Platform:: GPL1261
20 Samples

Download data: CEL

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Accession:: GSE62999

ID:: 200062999

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 54682.

Interleukin-33 effect on dual-specificity phosphatase 5-deficient bone marrow derived eosinophils

Analysis of BM-derived eosinophils isolated from dual-specificity phosphatase 5-deficient mice and stimulated with IL-33. DUSP5 is a growth factor‐inducible phosphatase preferentially expressed in immune cells. Results provide insight into the role of DUSP5 in IL-33 signaling in eosinophils.