On the Origin and Evolutionary Consequences of Gene Body DNA Methylation - - GEO DataSets

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On the Origin and Evolutionary Consequences of Gene Body DNA Methylation

(Submitter supplied) In plants, CG DNA methylation is prevalent in the transcribed regions of constitutively expressed genes (“gene body methylation; gbM”), but the origin and function of gbM remain unknown. Here we report the discovery that Eutrema salsugineum, has lost gbM from its genome, the first known instance for a flowering plant. Of all known DNA methyltransferases, only CHROMOMETHYLTRANSFERASE 3 (CMT3) is missing from E. more...

Organism:: Brassica rapa; Arabidopsis lyrata; Arabidopsis thaliana; Capsella rubella; Brassica oleracea; Eutrema salsugineum

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Third-party reanalysis