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Genome-wide mRNA expression and methylation patterns of neural genes in response to prenatal hormones

(Submitter supplied) We explored the molecular mechanisms that mediate changes in neural gene expression (i.e., hypothalamus and nucleus taenia of the amygdala) and aggression in male and female zebra finches (Taeniopygia guttata) exposed to prenatal testosterone. We used egg injections of testosterone or the vehicle to mimic maternal hormones, which are transferred to offspring during prenatal development. Many researchers have postulated that prenatal maternal hormones can generate adaptive phenotypic plasticity; however, no study has determined the mechanism facilitating these long-term changes. more...
Organism:
Taeniopygia guttata
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platform:
GPL22780
48 Samples
Download data: DIFF, TSV
Series
Accession:
GSE100396
ID:
200100396

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