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Probiotic consortia improve anti-viral immunity to SARS-CoV-2 in Ferrets [RT-PCR]

(Submitter supplied) Probiotics have been suggested as one solution to counter detrimental health effects by SARS-CoV-2, however, data so far is scarce. We tested the effect of two probiotic consortia, OL-1 and OL-2, against SARS-CoV2 in ferrets and assessed their effect on cytokine production and transcriptome in a human monocyte- derived macrophage (Mf) and dendritic cell (DC) model. The results showed that the consortia significantly reduced the viral load, modulated immune response, and regulated viral receptor expression in ferrets compared to placebo. more...
Organism:
Mustela putorius furo
Type:
Expression profiling by RT-PCR
Platform:
GPL30407
143 Samples
Download data: XLSX
Series
Accession:
GSE180390
ID:
200180390

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