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Molecular Signatures of HFpEF: Systems Biology in a Cardiac-Centric Large Animal Model

(Submitter supplied) In this study the authors used systems biology to define progressive changes in metabolism and transcription in a large animal model of heart failure with preserved ejection fraction (HFpEF). Transcriptomic analysis of cardiac tissue, 1 month post-banding, revealed loss of electron transport chain components, and this was supported by changes in metabolism and mitochondrial function, altogether signifying alterations in oxidative metabolism. more...
Organism:
Felis catus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24552
36 Samples
Download data: TXT
Series
Accession:
GSE181184
ID:
200181184

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