GEO DataSets

(Submitter supplied) A cDNA microarray composed of 9306 uniEST probes was constructed andapplied to detect the gene expression profile of protoscoleces of E. granulosus treated with dihydroartemisinin in vitro, respectively. Compared with the untreated protoscoleces, 752 genes were up-regulated and 269 genes were down-regulated in protoscoleces treated with dihydroartemisinin. The differential expression genes in protoscoleces induced by dihydroartemisinin were clustered into molecular metabolic process, cell development and differentiation, anatomical structure morphogenesis and formation, and were enriched in calcium signaling pathway, protein processing in endoplasmic reticulum (ER), molecular metabolism and synthesis, Wnt signaling pathway, MAPK signaling pathway, TGF-beta signaling pathway.

Organism:

Echinococcus granulosus

Type:

Expression profiling by array

Platform:

GPL30676

6 Samples

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